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A New Type of Regenerative Treatment: Transform Your Skin with Polynucleotide Technology

Here’s Everything You Need To Know About Polynucleotide Injections!

Polynucleotide treatment is now offered at House of Beauty, Camberley, UK

As skin matures, it often presents challenges such as diminished elasticity and the emergence of fine lines. These concerns, prevalent among many, call for a sophisticated and effective approach to skin rejuvenation. Traditional methods, while providing temporary relief, may not deliver comprehensive rejuvenation. Polynucleotide treatments emerge as a scientifically-backed solution, offering a new dimension in aesthetic medicine. Originating from natural DNA sources, Polynucleotides have garnered acclaim for their profound ability to stimulate skin regeneration at a cellular level. This advanced treatment transcends conventional anti-ageing methods by not only addressing visible signs but also enhancing the intrinsic health of your skin. With Polynucleotide treatments, you embark on a journey towards enhanced skin vitality, experiencing a naturally youthful and revitalised complexion.

At House of Beauty, we are delighted to introduce our exceptional Polynucleotide treatment, meticulously administered under the expert guidance of our founder, Anna Hannaford. Boasting over a decade of expertise in aesthetic beauty, Anna brings a wealth of knowledge and precision to each treatment. Her comprehensive training in the latest Polynucleotide techniques ensures that every session is customised to enhance your inherent beauty. Anna’s dedication to safety, efficacy, and personalised attention ensures a transformative journey for each client, culminating in a visibly rejuvenated and radiant complexion.

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What Are Polynucleotides?

Polynucleotides represent a groundbreaking advancement in aesthetic treatments, marking a significant shift in how we approach skin rejuvenation and anti-ageing therapies. At their core, polynucleotides are complex chains of nucleotides, the fundamental building blocks of DNA and RNA. This intricate molecular structure is pivotal in various biological processes, including cellular repair and regeneration. In the context of aesthetic medicine, polynucleotides harness these natural regenerative properties to offer a novel solution for skin revitalisation. Their emergence in the beauty industry is a testament to the evolving intersection of science and aesthetics, where innovative treatments are increasingly grounded in robust scientific principles.

The role of polynucleotides in aesthetic treatments is multifaceted and profoundly impactful. By stimulating the natural production of collagen and elastin, two vital proteins for maintaining skin elasticity and firmness, polynucleotide treatments effectively combat the visible signs of ageing. As we age, the natural production of these proteins diminishes, leading to the development of wrinkles, fine lines, and a loss of skin firmness. Polynucleotide treatments address these concerns at a cellular level, promoting skin health from within. This approach not only yields visible improvements in skin texture and tone but also aligns seamlessly with the body’s natural processes, ensuring results that are both effective and harmonious with the intrinsic properties of the skin.

How Do Polynucleotides Work?

Polynucleotides function through a sophisticated biological process, making them a key component in modern aesthetic treatments. These molecules, essential to DNA and RNA, have a unique role in skin rejuvenation and anti-ageing therapies. Their mechanism of action is multi-layered, involving several critical steps:

Collagen and Elastin Stimulation: Polynucleotides trigger the body’s natural production of collagen and elastin. Collagen provides structural support and firmness to the skin, while elastin contributes to its elasticity. The decline in these proteins due to ageing leads to wrinkles and skin laxity. Polynucleotides help reverse this by boosting the production of these essential proteins.

Improvement in Skin Hydration and Texture: They enhance the skin’s hydration levels and texture. This is achieved by improving the skin’s capacity to retain moisture, leading to a more hydrated and plump appearance.

Cellular Regeneration Promotion: Polynucleotides are effective in encouraging the repair and renewal of skin cells. This is particularly beneficial for skin damaged by environmental factors, helping to mitigate the effects of ageing accelerated by external stressors.

Integration with Natural Skin Processes: The treatment aligns with the body’s natural skin processes. This ensures that the enhancements are effective and maintain a natural appearance.

By stimulating collagen and elastin, polynucleotides not only improve the skin’s firmness and elasticity but also its ability to stay hydrated and smooth. This comprehensive approach to skin rejuvenation addresses various signs of ageing, making polynucleotide treatments a reliable option for those seeking effective skin care solutions. The treatment’s compatibility with the body’s own mechanisms ensures that the results are both impactful and harmonious with the natural properties of the skin, offering a rejuvenated appearance that feels as natural as it looks.

What Can Polynucleotides Be Used For?

Polynucleotide treatments cater to a diverse range of skin issues and conditions, leveraging their unique biological properties for effective results:

  • Reducing Ageing Signs: These treatments directly target common ageing signs like wrinkles, fine lines, and skin sagging.They stimulate collagen and elastin production, essential for maintaining skin firmness and elasticity.
  • Enhancing Skin Hydration and Texture: Polynucleotides significantly boost skin hydration and improve overall texture.They enhance the skin’s moisture retention capabilities, resulting in a plumper and smoother appearance.
  • Promoting Skin Rejuvenation and Regeneration: The treatments excel in rejuvenating and regenerating skin cells. They are particularly beneficial for skin that has suffered environmental damage, aiding in repair and renewal.
  • Addressing Scarring and Hyperpigmentation: Polynucleotides effectively reduce the appearance of scars, including those from acne, and help even out skin tone. They work on reducing hyperpigmentation, leading to a more uniform skin complexion.
  • Improving Skin Elasticity: The treatments contribute to enhanced skin elasticity. This benefit is especially noticeable in areas prone to elasticity loss, such as the under-eye region and neck.
  • Treating Sun-Damaged Skin: Polynucleotides are adept at treating sun-damaged skin, mitigating some effects of UV exposure. They improve skin texture and reduce the visibility of sunspots.
  • Revitalising Overall Skin Health: Beyond targeting specific issues, polynucleotide treatments offer holistic skin revitalisation.They improve the overall health and vitality of the skin, contributing to a rejuvenated appearance.

At A Glance

Procedure Time

45 minutes


Topical anaesthetic can be applied


Fine lines, wrinkles, skin hydration, and texture

Risks & Complications

Mild swelling/redness, rare allergic reactions




Improved skin texture and elasticity over weeks to months

Treatment needed

2-4 sessions for optimal results

Not Suitable For

Pregnant, breast-feeding individuals, or those receiving IVF treatment

How Do Polynucleotides Work In Anti-Ageing?

Polynucleotides tackle ageing at the cellular level, primarily by stimulating the production of collagen and elastin, the key proteins responsible for skin’s structure and elasticity. As skin matures, the natural generation of these proteins decreases, leading to visible ageing signs like wrinkles and sagging. Polynucleotides activate the skin’s fibroblasts, cells that produce collagen and elastin, resulting in an increase in these proteins. This boost not only enhances skin firmness but also diminishes the appearance of ageing signs.

In addition to firming the skin, polynucleotides significantly improve hydration. They work in conjunction with hyaluronic acid, a natural skin component known for retaining moisture. This synergy leads to better-hydrated skin, crucial for a youthful appearance and reducing signs like dryness and fine lines. Polynucleotides also accelerate the repair and renewal of skin cells, processes that naturally slow down with age. This cellular regeneration is especially beneficial for skin damaged by environmental factors, aiding in maintaining a healthy and youthful skin complexion.

What Are The Benefits Of Polynucleotide Treatments?

Polynucleotide treatments offer a range of benefits for the skin, addressing various concerns and enhancing overall skin health. Here are some of the key benefits:

Revitalised Skin Texture: Experience a noticeable improvement in skin texture. Polynucleotide injections refine the skin’s surface, leading to a smoother, more even complexion. They help in reducing roughness and improving the overall feel of the skin.

Enhanced Hydration for a Plumper Look: Discover the secret to deeply hydrated skin. These injections boost the skin’s ability to retain moisture, resulting in a plumper, more hydrated appearance. Well-hydrated skin not only looks healthier but also displays fewer signs of ageing such as dryness and fine lines.

Visible Reduction in Ageing Signs: Turn back the clock on ageing. Polynucleotide injections effectively reduce visible signs of ageing, including wrinkles, fine lines, and sagging skin. By stimulating collagen and elastin production, they restore skin firmness and elasticity, contributing to a more youthful appearance.

Improved Skin Elasticity and Firmness: Feel the firmness and elasticity return to your skin. The treatment enhances the skin’s natural elasticity, making it more resilient and firm. This benefit is particularly noticeable in areas that tend to lose elasticity over time, such as the under-eye region and neck.

Natural and Long-Lasting Results: Enjoy results that are both natural and enduring. Polynucleotide injections offer results that blend seamlessly with the skin’s natural properties. The improvements achieved are long-lasting, maintaining a natural and rejuvenated appearance over time.

Polynucleotide Treatment Before And After

What To Expect During Polynucleotide Treatment?

Embarking on a Polynucleotide treatment at House of Beauty is a journey tailored to your individual skin needs and aesthetic goals. Here’s what you can expect during the treatment process:

Initial Consultation: Your treatment journey begins with a one-on-one consultation with Anna. She will assess your skin, discuss your specific concerns, and understand your aesthetic goals. This session is essential for tailoring the treatment to your unique needs and setting realistic expectations.

Customised Treatment Plan: Based on the consultation, a customised treatment plan is developed. This plan is tailored to address your unique skin issues, whether it’s combating signs of ageing, improving hydration, or enhancing skin texture.

Pre-Treatment Preparation: Before the procedure, you’ll receive detailed instructions to prepare your skin. This may include guidelines on skincare routines or avoiding certain medications or supplements that could affect the treatment outcome.

The Treatment Session: On the day of the treatment, your skin will be cleansed and prepared. Polynucleotide injections are then carefully administered to the targeted areas discussed during your consultation. The procedure is minimally invasive, with a focus on comfort and precision.

Post-Treatment Care: After the injections, you’ll receive comprehensive aftercare instructions. These guidelines are designed to maximise the treatment benefits and ensure a smooth recovery. You might be advised to avoid certain activities or skincare products for a short period post-treatment.

Scheduled Follow-Up: House of Beauty provides ongoing support and follow-up appointments. These sessions are important for monitoring your progress and making any necessary adjustments to the treatment plan.

At House of Beauty, we ensure that each step of the Polynucleotide treatment is conducted with the utmost care and professionalism. Our goal is to provide you with a comfortable experience and results that enhance your natural beauty, leaving your skin rejuvenated and naturally beautiful.

Polynucleotide Treatment Aftercare

Ensuring the best results from your Polynucleotide treatment involves a dedicated aftercare routine. At House of Beauty, we provide detailed guidance to help you through your recovery and maximise the benefits of the treatment:

  1. Soothe and Protect Your Skin Immediately After Treatment: It’s common to experience mild swelling or a bit of redness in the treated areas. Gently apply a cold compress to alleviate these symptoms, but be careful not to exert too much pressure on the skin. Avoid touching or massaging the treated areas to prevent any disturbance to the newly injected polynucleotides.
  2. Carefully Plan Your Activities and Skincare: In the first 24 to 48 hours following your treatment, it’s advisable to avoid strenuous exercise and exposure to high temperatures, like saunas or hot baths. Protect your skin from direct sunlight. Using a broad-spectrum sunscreen is essential to safeguard the treated areas from UV damage.
  3. Maintain Hydration and Follow a Nutritious Diet: Keeping your body well-hydrated is crucial. Drink plenty of water to support the skin’s hydration levels. Incorporate a diet rich in vitamins and antioxidants to aid in the skin’s healing and rejuvenation process.
  4. Follow Up for Continued Care: House of Beauty schedules a follow-up appointment to monitor your progress and ensure optimal healing. This session is an opportunity to address any questions and to make sure your recovery is on track.
  5. Long-Term Skin Care and Maintenance: After the initial recovery period, continue to care for your skin with a gentle and nourishing skincare routine. Regular moisturising and protection against environmental factors will help maintain the results of your treatment.

How Long Does It Take for Polynucleotide Treatment to Work?

The timeline for visible results from Polynucleotide treatments can vary, depending on individual skin types and the specific concerns being addressed. Generally, clients begin to notice improvements within a few weeks after the initial treatment. The full effects, however, typically become more apparent over the course of several months. This gradual progression is due to the nature of polynucleotides, which work by stimulating the body’s natural processes of collagen and elastin production, as well as enhancing cellular regeneration.

As these processes take time, the skin’s appearance improves incrementally. Most clients observe a noticeable difference in skin hydration, texture, and elasticity within the first month, with continued improvements in firmness and a reduction in fine lines and wrinkles over the following months. It’s important to note that multiple treatment sessions may be necessary to achieve optimal results, and these should be spaced out. The longevity and effectiveness of the treatment are also influenced by factors such as lifestyle, skin care routine, and overall health, making it essential to follow post-treatment care instructions and maintain a healthy lifestyle for lasting results.

Are There Any Side-Effects with Polynucleotides?

Understanding potential side effects and safety considerations is crucial when opting for Polynucleotide treatments. While these treatments are generally safe and well-tolerated, as with any medical procedure, there are certain risks and side effects that clients should be aware of:

  • Injection Site Reactions: Common side effects include redness, swelling, bruising, and tenderness at the injection sites. These are typically mild and resolve within a few days after the treatment.
  • Allergic Reactions: Allergic reactions to components in the polynucleotide formula, though rare, can occur. Discussing any known allergies with Anna Hannaford before treatment is essential.
  • Infection Risk: There is a small risk of infection associated with any injection-based treatment. Anna Hannaford ensures the highest standards of hygiene and safety to minimize this risk.
  • Temporary Discomfort: Some clients may experience temporary discomfort or itching at the injection sites, which usually subsides quickly.
  • Rare Complications: On very rare occasions, more serious complications like granuloma formation or vascular complications can occur. These risks are significantly reduced when the treatment is administered by an experienced professional like Anna Hannaford.


It’s important to have a thorough consultation before undergoing Polynucleotide treatments to understand all potential risks and side effects. After your treatment, a detailed aftercare instructions will be given to manage any side effects effectively, ensuring a safe and successful treatment experience.

How Much Does Polynucleotide Treatment Cost?

Embrace the path towards enhanced skin health and rejuvenation with our Polynucleotide treatments. Here at House of Beauty, we offer tailed treatments at these pricings:

Face Treatment: £250

  • Our facial Polynucleotide treatment targets signs of ageing, improves hydration, and enhances overall skin texture, providing a rejuvenated and youthful appearance.


Eye Treatment: £250

  • Specifically focusing on the delicate eye area, this treatment reduces fine lines, wrinkles, and improves skin elasticity, giving a refreshed and revitalised look.


Our pricing is structured to ensure you receive the best in skin care, combining advanced techniques with premium polynucleotide products.

To get started, schedule a short initial consultation with our senior injector. During this consultation, Anna will work with you to tailor a personalised treatment best suited for your aesthetic desires.

What Are the Best Polynucleotides Injections?

Here are some of the most popular polynucleotide injections, each known for their unique benefits and applications in skin rejuvenation:

Plinest stands out with its polynucleotides derived from trout fish. It addresses a broad spectrum of skin concerns, effectively targeting fine lines, wrinkles, volume loss, and is also suitable for sensitive skin. Plenist is beneficial in reducing acne scars, hyperpigmentation, and refining enlarged pores.

Plenhyage utilises salmon-derived polynucleotides and is renowned for its hydrating properties, as well as its ability to improve lines, wrinkles, and provide a lifting effect. It is particularly effective for treating hollow eyes, dehydrated skin, and stretch marks. The treatment involves a series of four sessions, with results typically becoming visible three months after the course is completed.

Nucleofill focuses on skin renewal and bio-restructuring derived from salmon DNA. It offers lifting, antioxidant, and moisturising benefits, stimulating cell renewal and collagen production. This makes it suitable for skin affected by oxidative stress, dehydration, stretch marks, and scars.

Vitaran is a 100% quality-controlled polynucleotide injectable derived from purified salmon DNA. It is a bio-revitalising skin injectable with anti-inflammatory properties, stimulating the synthesis of collagen, elastin, and hyaluronic acid. Vitaran is particularly effective for skin rejuvenation and repair, scar improvement, and combating free radical damage.

Each of these polynucleotide injections offers unique benefits, catering to different skin rejuvenation needs. It is important to consult with a qualified practitioner like Anna Hannaford to determine which polynucleotide injection is best suited for your skin concerns and goals.

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Frequently Asked Questions

What Are Polynucleotides?

Polynucleotides are natural compounds, essential components of DNA and RNA, used in aesthetic treatments for skin rejuvenation. They stimulate the body’s natural regenerative processes, enhancing skin health and appearance.

What Are Polynucleotides Made From?

Polynucleotides are made from nucleotides, the building blocks of DNA and RNA. They are typically derived from natural sources, such as trout or salmon DNA, and are purified for use in skin treatments.

How Do Polynucleotides Work?

Polynucleotides work by stimulating collagen and elastin production, enhancing skin hydration, and promoting cellular regeneration. This leads to improved skin texture, elasticity, and a reduction in signs of ageing.

What Are Polynucleotides Used to Treat?

Polynucleotides treat a range of skin issues, including fine lines, wrinkles, loss of elasticity, dehydration, and overall skin dullness. They are effective in overall skin rejuvenation.

What Can You Expect to See After Polynucleotide Treatment?

After polynucleotide injections, expect to see improved skin hydration, texture, and elasticity. Signs of ageing like fine lines and wrinkles will diminish, leading to a more youthful and revitalised appearance.

How Long Do Polynucleotide Treatments Take?

Polynucleotide treatments typically take a few weeks to show visible results, with full effects becoming more apparent over several months. The skin gradually improves in texture, firmness, and hydration.

Which Polynucleotide Treatments Do You Use?

At House of Beauty, we use clinically proven polynucleotide treatments like Plinest and Plenhyage, tailored to individual skin needs for optimal rejuvenation and results.

Is There Any Downtime or Side Effects with Polynucleotide Treatments?

Polynucleotide treatments have minimal downtime. Common side effects include mild swelling or redness at injection sites, which subside quickly. The treatments are generally well-tolerated.

Do Polynucleotide Treatments Hurt?

Polynucleotide treatments involve minimal discomfort. A numbing cream may be applied to ease any slight pain during the injection process.

What’s PDRN? Are They Polynucleotides, Too?

Polydeoxyribonucleotides (PDRN) are a subtype of polynucleotides (PN). Both PDRN and PN are known for their healing and anti-ageing effects, with PDRN specifically being a shorter chain of DNA that aids in skin regeneration and repair.

How Many Sessions Of Polynucleotide Do I Need?

The number of polynucleotide treatments needed varies based on individual skin conditions and goals. Typically, a series of treatments are recommended for best results.

Can I Use Polynucleotides Alongside Other Treatments?

Yes, polynucleotides can be used alongside other treatments like laser therapy, microneedling, and dermal fillers, often enhancing overall results.

Who Should Avoid Polynucleotide Treatment?

Individuals with allergies to the treatment components, active skin infections, or certain medical conditions should avoid polynucleotide treatments. A consultation is essential to determine suitability.

How Different Are Polynucleotides from Skin Boosters?

Polynucleotides and skin boosters differ primarily in their mechanism of action. Polynucleotides work at a cellular level to stimulate the natural production of collagen and elastin, thereby improving skin elasticity and reducing signs of ageing. Skin boosters like Profhilo, on the other hand, primarily hydrate and improve skin texture by delivering hyaluronic acid and other nutrients directly into the skin.

How Different Are Polynucleotides from Dermal Fillers?

Polynucleotides and dermal fillers serve different purposes in aesthetic treatments. Polynucleotides focus on enhancing the skin’s natural regenerative processes, leading to improved skin texture, elasticity, and overall health over time. Dermal fillers provide immediate results by adding volume and contouring specific areas of the face.

How Does a Polynucleotide Treatment Rejuvenate the Under Eyes?

Polynucleotide treatment rejuvenates the under-eye area by improving skin elasticity, reducing fine lines, and enhancing hydration, leading to a fresher, more youthful appearance.

Beauty Salon House of Beauty Camberley

Ready for Your Beauty Transformation?

House of Beauty is here to offer the support you need. Your journey begins by scheduling a consultation with our experienced injector, Anna, who is dedicated to listening, guiding, and assisting you in making well-informed decisions about your beauty goals. Begin your confident journey towards enhancing your natural beauty today. Your transformation awaits, and we’re here to ensure it’s a smooth and rewarding experience.

House of Beauty is located in Camberley, with free parking available and is easily accessed from the M3. Our clients come from surrounding areas including Farnborough,  Aldershot and further afield including  Ascot, Windsor, Bracknell, Guildford and Woking.